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[13] In response to these studies and their perceived threat to the tobacco industry's future profitability, tobacco companies experimented with new modifications to the cigarette design

And to fast forward to today, we have taken final action, one way or the other, on more than 6.6 million of the almost 6.7 million products that were the subject of timely submitted applications

In the early 1600s, James I of England wrote that tobacco was dangerous to the lungs,[1] and yet hundreds of years later, tobacco companies in the USA were using doctors to promote the idea that smoking was safe

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